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Are you looking to book up a cruise? Then look at our Mediterranean cruises departing from Rome. Thanks to this amazing trip, you can take in one of the most amazing cities in the world. At the same time, you can easily take in what was once a prime seat of governance for much of Europe. It’s for this reason that Rome is such a fine city to begin any cruise from.

You are not only guaranteed to have a tremendous time at sea; you are going to enjoy a much more satisfying experience overall. The end result? Absolute bliss!

We see many people booking up Mediterranean cruises departing from Rome today. The reason why is simple; they wish to take in much of the Mediterranean, but also experience one of its crown jewels. If you want to make sure that you have a tremendous time at sea whilst taking in the richness of Roman life, then book up for this kind of Mediterranean cruise.

You’ll be able to take in the richness of Rome and all that it offers. It also allows you the time that you need to really put in place the perfect starting point for transport.

Mediterranean Cruises Departing from Rome

One of the most challenging aspects of getting involved with any kind of Mediterranean cruise is setting up where to start. With Rome, you know that you are setting off on your journey from a rich and engrossing city. The kind of cultural capital that makes it easy for you to appreciate both past and present.

From the depth of the ancient architecture to the amazing venues that still stand from the Roman Empire, you’ll find yourself surrounded by a marvellous city. Add in the fact that you can experience everything from a trip to the Coliseum to the modern equivalent in the Stadio Olimpico, home to AS Roma and SS Lazio, two of the most prominent Italian football clubs.

Outside of culture and sport, Rome is a city with a rich nightlife and a tremendous cultural heart. From exploring old museums and seeing sights of what was once the hub of the most powerful empire on the planet, this gives you a way to enjoy a truly iconic capital of European culture.
From one capital, you then head to the next. Our Mediterranean cruises departing from Rome take in all manner of locations across the Mediterranean. This allows you to compare and contrast some of the richest and most stunning cities in the world, making it easy for you to put together a truly remarkable experience.
You can sail to all manner of different locations, too. Simply take a look at the options we have, and book up the Mediterranean cruise for you. Not only that, but this makes it very easy for you to make the right call and to start really moving forward with a dream vacation.
Don’t just settle for either Rome or the Mediterranean; combine both in a special cruise!

Rome to Fort Lauderdale
 Thursday 28th November 2024
Departing Rome (Civitavecchia)  
 21 Nights
 Viking Sky
 Twin From $12,091 pp
 Single From $24,182 pp
Rome to Miami
 Thursday 28th November 2024
Departing Rome (Civitavecchia)  
 16 Nights
 Scarlet Lady
 Adult Only Cruise Line
 Twin From $2,879 pp
 Single From $5,556 pp
Italy, France & Spain
 Tuesday 3rd December 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Lirica
 Luxury Large Ship Cruises
 Twin From $2,071 pp
 Quad From $1,693 pp
Rome to Fort Lauderdale
 Wednesday 4th December 2024
Departing Rome (Civitavecchia)  
 18 Nights
 Island Princess
Sale Fare  Sale Fare
 Premium Cruise Line
 Twin From $1,572 pp
 Single From $2,929 pp
Italy, Valletta, Barcelona & Marseille
 Monday 9th December 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC World Europa
 Luxury Large Ship Cruises
 Twin From $1,217 pp
 Quad From $1,921 pp
Italy, France & Spain
 Tuesday 10th December 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Lirica
 Luxury Large Ship Cruises
 Twin From $839 pp
 Quad From $883 pp
Italy, Valletta, Barcelona & Marseille
 Monday 16th December 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC World Europa
 Luxury Large Ship Cruises
 Twin From $1,654 pp
 Quad From $2,323 pp
Italy, France & Spain
 Tuesday 17th December 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Lirica
 Luxury Large Ship Cruises
 Twin From $1,179 pp
 Quad From $1,780 pp
Italy, Valletta, Barcelona & Marseille
 Monday 23rd December 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC World Europa
 Luxury Large Ship Cruises
 Twin From $1,838 pp
 Single From $3,138 pp
Italy, France & Spain
 Tuesday 24th December 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Lirica
 Luxury Large Ship Cruises
 Twin From $1,499 pp
 Quad From $2,333 pp
Rome (Civitavecchia) to Marseille
 Friday 27th December 2024
Departing Rome (Civitavecchia)  
 3 Nights
 MSC Magnifica
 Twin From $1,093 pp
 Quad From $1,208 pp
Italy, Marseille & Spain
 Friday 27th December 2024
Departing Rome (Civitavecchia)  
 8 Nights
 MSC Magnifica
 Luxury Large Ship Cruises
 Twin From $2,438 pp
 Single From $4,377 pp
Italy, Valletta, Barcelona & Marseille
 Monday 30th December 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC World Europa
 Luxury Large Ship Cruises
 Twin From $2,313 pp
 Single From $3,148 pp
Italy, France & Spain
 Tuesday 31st December 2024
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Lirica
 Luxury Large Ship Cruises
 Twin From $1,867 pp
 Quad From $2,537 pp
World Cruise
 Saturday 4th January 2025
Departing Rome (Civitavecchia)  
 120 Nights
 MSC Magnifica
 Twin From $30,839 pp
 Quad From $23,984 pp
Rome to Rio de Janeiro
 Saturday 4th January 2025
Departing Rome (Civitavecchia)  
 18 Nights
 MSC Magnifica
 Twin From $2,933 pp
 Single From $4,982 pp
Rome to Buenos Aires
 Saturday 4th January 2025
Departing Rome (Civitavecchia)  
 22 Nights
 MSC Magnifica
 Twin From $3,625 pp
 Single From $6,294 pp
Rome to Barcelona
 Saturday 4th January 2025
Departing Rome (Civitavecchia)  
 3 Nights
 MSC Magnifica
 Twin From $803 pp
 Single From $1,372 pp
Rome to Valparaiso
 Saturday 4th January 2025
Departing Rome (Civitavecchia)  
 37 Nights
 MSC Magnifica
 Twin From $6,385 pp
 Single From $11,544 pp
Malta, Spain & France
 Monday 6th January 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC World Europa
 Luxury Large Ship Cruises
 Twin From $1,343 pp
 Quad From $1,731 pp
Italy, France & Spain
 Tuesday 7th January 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Lirica
 Luxury Large Ship Cruises
 Twin From $713 pp
 Quad From $742 pp
Malta, Spain & France
 Monday 13th January 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC World Europa
 Luxury Large Ship Cruises
 Twin From $1,373 pp
 Quad From $1,518 pp
Italy, France & Spain
 Tuesday 14th January 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Lirica
 Luxury Large Ship Cruises
 Twin From $713 pp
 Quad From $752 pp
Malta, Spain & France
 Monday 20th January 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC World Europa
 Luxury Large Ship Cruises
 Twin From $1,518 pp
 Quad From $1,494 pp
Italy, France & Spain
 Tuesday 21st January 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Lirica
 Luxury Large Ship Cruises
 Twin From $810 pp
 Quad From $825 pp
Malta, Spain & France
 Monday 27th January 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC World Europa
 Luxury Large Ship Cruises
 Twin From $1,198 pp
 Quad From $1,494 pp
Italy, France & Spain
 Tuesday 28th January 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Lirica
 Luxury Large Ship Cruises
 Twin From $713 pp
 Quad From $863 pp
Malta, Spain & France
 Monday 3rd February 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC World Europa
 Luxury Large Ship Cruises
 Twin From $1,082 pp
 Quad From $1,319 pp
Italy, France & Spain
 Tuesday 4th February 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC Lirica
 Luxury Large Ship Cruises
 Twin From $810 pp
 Quad From $1,004 pp
Malta, Spain & France
 Monday 10th February 2025
Departing Rome (Civitavecchia)  
 7 Nights
 MSC World Europa
 Luxury Large Ship Cruises
 Twin From $1,343 pp
 Quad From $1,426 pp